Human microsporidiosis

Molecular Epidemiology of Human Microsporidiosis Caused by Enterocytozoon Bieneusi

Enterocytozoon bieneusi is a common human pathogen, responsible for more than 90% of overall human microsporidian infections. The epidemiology of E. bieneusi infections, however, is not well studied, and little is known about its transmission routes. Enterocytozoon bieneusi-like spores have been reported in surface and ground water in the United States and France, and a possible outbreak of mic...

Microsporidiosis in zebrafish

Waterborne Outbreak of Microsporidiosis

host cellular immune response among HTLV-I carriers. In data published elsewhere, we documented subclinical immunosuppression on the basis of the association of HTLV-I infection with reduced response to the tuberculin-purified protein derivative (PPD) recall antigen [3, 4]. In vitro studies suggest that the nonresponsiveness to PPD in these HTLV-I carriers may be related to a lack of IFN-g prod...

Microsporidiosis in zebrafish research facilities.

Pseudoloma neurophilia (Microsporidia) is the most common pathogen detected in zebrafish (Danio rerio) from research facilities. The parasite infects the central nervous system and muscle and may be associated with emaciation and skeletal deformities. However, many fish exhibit subclinical infections. Another microsporidium, Pleistophora hyphessobryconis, has recently been detected in a few zeb...

Microsporidiosis in Vertebrate Companion Exotic Animals

Veterinarians caring for companion animals may encounter microsporidia in various host species, and diagnosis and treatment of these fungal organisms can be particularly challenging. Fourteen microsporidial species have been reported to infect humans and some of them are zoonotic; however, to date, direct zoonotic transmission is difficult to document versus transit through the digestive tract....